2010 Mercedes-Benz E350 Service and Repair Manual

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Factory-Grade Data

2010 Mercedes-Benz E350 service and repair manual — a detailed, factory-style reference for maintenance, diagnostics, and repair. Use it to confirm correct procedures, specifications, and system coverage before you start work.

Designed for technicians and DIY owners, this manual helps you troubleshoot accurately, follow step-by-step repair procedures, and reference wiring diagrams and system sections quickly while you work.

What’s included

  • Step-by-step repair procedures and service information
  • Specifications and reference data (where provided)
  • Wiring diagrams and electrical sections
  • Powertrain, brakes, steering, suspension, HVAC and more

Trims covered

  • Elegance Sedan 4-Door
  • Base Sedan 4-Door
  • 4Matic Sedan 4-Door
  • Sport Sedan 4-Door
  • Base Coupe 2-Door

Engines covered

  • 3.5L 3498CC V6 GAS DOHC Naturally Aspirated

Index / Table of contents

  • Body
  • Brakes
  • Chassis Electrical
  • Driveline
  • Engine Cooling
  • Engine Electrical
  • Engine Mechanical
  • Engine Performance & Emission Controls
  • Fuel System
  • General Information & Identification
  • Heating, Ventilation, & Air Conditioning
  • Hybrid & Electric Vehicle Systems
  • Steering
  • Suspension
  • Transmission, Clutch, & Transfer Case
  • Wiring Diagrams

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Vehicle Safety Data

2010 Mercedes-Benz E350 Recalls & Complaints

NHTSA #16V36300026/05/2016Component: AIR BAGS:FRONTAL:PASSENGER SIDE:INFLATOR MODULE

Mercedes-Benz USA, LLC (MBUSA) is recalling certain model year 2008-2011 C300 Sedan, C300 4matic Sedan, C350 Sedan, C63 AMG Sedan vehicles, 2010-2011 GLK350, GLK350 4-Matic and E350 Coupe vehicles, 20

Consequence

An inflator rupture may result in metal fragments striking the vehicle occupants resulting in seriou

Remedy

MBUSA will notify owners, and dealers will replace the passenger frontal air bag modules, free of ch

NHTSA #22V16800018/03/2022Component: EXTERIOR LIGHTING:LIGHTING CONTROL MODULE:SOFTWARE

Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2010 E350, 2014 G550, 2008-2009 C300, 2008 C350, 2009 CLK550, 2007 SL550, SLK280, and 2008 SLK350 vehicles. Various control units may have been upd

Consequence

Various system failures, such as loss of drive power, reduced exterior lighting, or loss of dynamic

Remedy

Dealers will update the software configuration on the affected control units, free of charge. Owner

NHTSA #16V08100011/02/2016Component: AIR BAGS:FRONTAL:DRIVER SIDE:INFLATOR MODULE

Mercedes-Benz USA, LLC. (MBUSA) is recalling certain model year 2009-2010 ML320 BlueTec 4Matic, GL320 BlueTec 4Matic and R320 CDI 4Matic, 2011 E350 Cabriolet and E550 Cabriolet, 2009-2011 ML350, ML35

Consequence

In the event of a crash necessitating deployment of the driver's frontal air bag, the inflator could

Remedy

MBUSA will their notify owners, and Fiat Chrysler will notify the affected Chrysler owners. Dealers

TSB #11031654

In our continuing efforts to assure the proper performance of Mercedes-Benz products and to enhance the satisfaction of our customers, Mercedes-Benz USA (MBUSA) is extending the warranty coverage on the fuel filter unit for Partial Zero Emi

TSB #11031648

Mercedes-Benz USA, LLC will provide an Extended Modification Warranty for each vehicle that has received the Approved Emission Modification. The Extended Modification Warranty period shall be the greater of: (i) 10 years from the date of in

TSB #11031643

To enhance the satisfaction of our customers, avoid further costs of litigation and return focus to its core businesses, Mercedes-Benz USA, LLC (MBUSA) has entered into a settlement regarding claims relating to allegations that the Burl Wal

TSB #11031594

This NCU replaces the prior NCUs issued on May 18, June 25, 2020 and October 1, 2020 and contains important workshop instructions on how the HVAC Service Warranty repair must be carried out. To enhance the satisfaction of our customers, avo

TSB #11031588

In our continuing efforts to assure the proper performance of Mercedes-Benz products and to enhance the satisfaction of our customers, Mercedes-Benz USA, LLC (MBUSA) is extending the warranty coverage on the fuel filter unit in certain Mode

TSB #11031580

Complaint Headlamp, front fog lamp leaky or fogged. Cause Fogging of the headlamps is a natural phenomenon, which can occur under certain climatic conditions. It does not lead to any technical impairment of the headlamp. If a pressure compe

TSB #11029959

Complaint Headlamp, front fog lamp leaky or fogged Cause Fogging of the headlamps is a natural phenomenon, which can occur under certain climatic conditions. It does not lead to any technical impairment of the headlamp. If a pressure compen

TSB #11029062

Complaint Headlamps leaking or fogged Cause The fogging of the headlamp is a natural phenomenon which can occur under certain climatic conditions. In contrast to a leaky headlamp, physical fogging does not result in a technical impairment o

Showing the 8 most recent of 175 technical service bulletins on file with NHTSA.

20140825Component: STRUCTURE:BODYCrash reported2 injured

ANOTHER CAR MADE AN ILLEGAL U-TURN AND CAUSED ME TO T-BONE ON HIS PASSENGER SIDE. FRONT OF MY CAR HIT HIS PASSENGER SIDE AND DRAGGED HIS CAR FOR ABOUT 10 FEET. AIR BAGS ON MY CAR DID NOT DEPLOY, SAFET

20140825Component: SUSPENSIONCrash reported2 injured

ANOTHER CAR MADE AN ILLEGAL U-TURN AND CAUSED ME TO T-BONE ON HIS PASSENGER SIDE. FRONT OF MY CAR HIT HIS PASSENGER SIDE AND DRAGGED HIS CAR FOR ABOUT 10 FEET. AIR BAGS ON MY CAR DID NOT DEPLOY, SAFET

20140825Component: ENGINECrash reported2 injured

ANOTHER CAR MADE AN ILLEGAL U-TURN AND CAUSED ME TO T-BONE ON HIS PASSENGER SIDE. FRONT OF MY CAR HIT HIS PASSENGER SIDE AND DRAGGED HIS CAR FOR ABOUT 10 FEET. AIR BAGS ON MY CAR DID NOT DEPLOY, SAFET

20241111Component: AIR BAGSCrash reported1 injured

I was involved in a head on collision when a motorist driving in the wrong lane hit the front of my car in the evening of 10/2/24. The impact was huge and my car was totaled. However, my airbag did no

20150205Component: AIR BAGSCrash reported1 injured

TL* THE CONTACT OWNED A 2010 MERCEDES BENZ E350. WHILE PROCEEDING THROUGH A GREEN LIGHT, A SNOW PLOW SPED THROUGH A RED LIGHT AND CRASHED INTO THE FRONT DRIVER SIDE OF THE CONTACT'S VEHICLE. THE AIR B

Showing the 5 most serious of 229 complaints filed with NHTSA.

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