2006 Mercedes-Benz E350 Service and Repair Manual

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This factory service and repair manual for the 2006 Mercedes-Benz E350 centers on one powertrain, a naturally aspirated 3.5L V6 that burns gasoline and uses double overhead camshafts. Around it, the year offers a 4-door sedan and a 4-door wagon, plus four trims: Base, 4Matic, Elegance and Sport. Service work on the engine and on both bodies is supported with specifications, torque values and wiring diagrams.

Engines covered

  • 3.5L V6 — DOHC, naturally aspirated, gasoline

Body styles covered

  • 4-door wagon
  • 4-door sedan

Trims covered

  • Base
  • 4Matic
  • Elegance
  • Sport

Known issues on the 2006 E350. Owners lodged 397 complaints about the 2006 E350; the fuel and propulsion system accounts for 145, the gasoline fuel system for 80 and the engine for 47. Thirteen complaints reported a crash, 11 an injury and 7 a fire, and one reported at least one death. The sunroof glass is behind the four recalls NHTSA lists for certain 2006 E350 vehicles: the panel could come loose because it was not properly fastened or because its bond to the sliding roof frame weakened, and dealers inspected it and replaced the roof where needed. Against the 2006 E-Class line, NHTSA filed a separate recall for certain vehicles whose software coding, entered during a workshop visit, was wrong and could stop the fuel pump switching off after a crash. Fuel system and roof diagnostics sit alongside procedures, torque values and wiring diagrams.

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