TSB: Some 2020 ? 2022 model year vehicles equipped with 17CY+ Panasonic Audio (versions less than 1226) and Navigation (versions less than 1225 or 1245 with 20 Teammate) may exhibit one or more of the following conditions: ?Navigation reset
2021 Lexus IS 350 Service and Repair Manual
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Covers Every System & ComponentEvery procedure for the 2021 Lexus IS 350
2021 Lexus IS 350 service and repair manual — a detailed, factory-style reference for maintenance, diagnostics, and repair. Use it to confirm correct procedures, specifications, and system coverage before you start work.
Designed for technicians and DIY owners, this manual helps you diagnose issues correctly, follow proven repair steps, and use wiring diagrams and system sections to track faults faster.
What’s included
- Step-by-step repair procedures and service information
- Specifications, torque values, and reference data
- Electrical diagnostics with full wiring diagrams
- Coverage across major systems: engine, transmission/driveline, brakes, steering, suspension, HVAC, and more
- Diagnostic trouble codes and troubleshooting flow
- Maintenance schedules and fluid capacities
Trims covered
- AWD
- RWD
Index / Table of contents
- Body
- Brakes
- Chassis Electrical
- Driveline
- Engine Cooling
- Engine Electrical
- Engine Mechanical
- Engine Performance & Emission Controls
- Fuel System
- General Information & Identification
- Heating, Ventilation, & Air Conditioning
- Maintenance & Lubrication
- Specifications
- Steering
- Suspension
- Transmission, Clutch, & Transfer Case
- Diagnostic Trouble Codes
- Technical Service Bulletins
- Wiring Diagrams
Payment & Security
Payment methods
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2021 Lexus IS 350 Recalls & Complaints
OBSOLETE NOTICE February 14, 2023: This bulletin is now obsolete. Please see L-SB-0007-23
TSB: Some 2018 ? 2022 model year Lexus vehicles equipped with the Enform? 2.0 Navigation System, require a Special Service Tool (SST) USB flash drive to update the map, points of interest, and system software. The SST is used with applicabl
TSB: This Service Bulletin provides a procedure to properly perform the Techstream ?Control the Injection Mode? active test in some 2016 ? 2022 model year Lexus vehicles equipped with an FKS engine
TSB: Some 2013 ? 2022 model year Lexus vehicles equipped with a 2WD drivetrain and the F Sport package may exhibit a clicking noise from the front wheel area during slow (parking lot) speed turns. The clicking noise that can be heard during
TSB: This Service Bulletin provides a procedure to properly perform the Techstream ?Control the Injection Mode? active test in some 2016 ? 2022 model year Lexus vehicles equipped with an FKS engine
TSB: Some 2013 ? 2022 model year Lexus vehicles equipped with a 2WD drivetrain and the F Sport package may exhibit a clicking noise from the front wheel area during slow (parking lot) speed turns. The clicking noise that can be heard during
DP: Due to improper programming of the Data Communication Module (DCM), which provides cellular communication in various situations, including emergencies, the driver and Safety Connect operator may not be able to hear each other?s voices d
Showing the 8 most recent of 60 technical service bulletins on file with NHTSA.
Other Years of the Lexus IS 350
Need a manual for a different year? Browse every Lexus IS 350 we cover.

2025
Lexus IS 350
$53.99

2024
Lexus IS 350
$53.99

2023
Lexus IS 350
$53.99

2022
Lexus IS 350
$53.99

2020
Lexus IS 350
$53.99

2019
Lexus IS 350
$53.99

2018
Lexus IS 350
$53.99

2017
Lexus IS 350
$53.99

2016
Lexus IS 350
$53.99

2015
Lexus IS 350
$53.99

2014
Lexus IS 350
$53.99

2013
Lexus IS 350
$53.99
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